18575801_SY 25 Jun 2016 19:35 Contribution non évaluée |
In conclusion, the predicted protein CTP synthetase function in this bacteria is to form cytoskeletal filaments and not the catalysis of UTP to CTP for RNA synthesis as it is localized in the cytoplasmic membrane instead of the cytosol.
References
- Ingerson-Mahar, M., Briegel, A., Werner, J. N., Jensen, G. J., & Gitai, Z. (2010). The metabolic enzyme CTP synthase forms cytoskeletal filaments. Nature Cell Biology, 12(8), 739-746. doi:10.1038/ncb2087
- Barry, R. M., Bitbol, A., Lorestani, A., Charles, E. J., Habrian, C. H., Hansen, J. M., … Gitai, Z. (2014). Large-scale filament formation inhibits the activity of CTP synthetase. eLife, 3. doi:10.7554/elife.03638
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